Mary Ann Chappel

  General Notes:

Roger Size notes:
I have a death certificate for Richard CHAPPELL b 1834 d 1898. Richard died of tuberculosis, like his older brother William and father, Richard.
I recently ordered the DC as I am compiling a chart of those in our family that are affected by Alport's Syndrome. A number of Mary Ann's children inherited the gene mutation that leads to Kidney failure, including my great grandfather, William Paull. I also have the mutated gene which is why I have a personal interest.

Are you aware of any descendants of James CHAPPEL having this syndrome? I understand that people may not like to admit to it, but I am just curious. It is an x-link gene mutation, and does not generally pass from father to son, so it is possible only Mary Ann and her older sister, Eliza(beth) Jane were carriers of tyhe mutated gene......presuming they had the same father.

I am resuming my search for Eliza Jane CHAPPLE b Oct1837, to see if any of her descendants are affected. She has been a tough nut to crack and has eluded Chris Unwin and myself for some years now. I am re-checking Chris's notes to see if we have missed anything. If the UK records have been exhausted I will look at Australian records, given James and Thomas emmigrated to Australia in ??? and 1856 respectively. Maybe Eliza(beth) Jane came out with them or around the same time?

  Noted events in her life were:

• source. Roger Size